The choice of catecholamines in septic shock: more and more good arguments to strengthen the known position, but don't lose the faith!

نویسنده

  • Andreas Meier-Hellmann
چکیده

The choice of catecholamines for hemodynamic stabilisation in septic shock patients has been an ongoing debate for several years. Several studies have investigated the regional effects in septic patients. Because of an often very small sample size, because of inconsistent results and because of methodical problems in the monitoring techniques used in these studies, however, it is not possible to provide clear recommendations concerning the use of catecholamines in sepsis. Prospective and adequate-sized studies are necessary because outcome data are completely lacking.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The effect of physiologic dose of intravenous hydrocortisone in patients with refractory septic shock: a randomized control trial

Objective: Septic shock is a response to infection and tissue hypoperfusion which does not respond to fluid therapy and eventually leads to organ dysfunction. Aggressive treatment of a broad-spectrum antimicrobial and supportive measures are the cornerstones of successful treatment. In addition to the main treatment, there are adjunctive therapies. Steroids are one of the treat...

متن کامل

The effect of selenase on the disease process of patients with septic shock admitted to the intensive care unit: A clinical trial in Tehran

  Purpose: Despite discovering new antibiotics, mortality due to septic shock has remained high.   This research has examined the effect of selenase in patients with septic shock admitted to the   intensive care unit (ICU) of a hospital in Tehran.   Materials and Methods: This double-blind clinical trial was done on 80 participants (40 case   and 40 control) who were admitted to the ICU with se...

متن کامل

Recently published papers: Sepsis – guidelines, treatment and novel approaches

The choice of inotropic agent, particularly in catecholamine-resistant septic shock, remains an area of debate. Here we discuss a recent trial examining the use of vasopressin in a carefully controlled trial setting. Yet more data on the use of drotrecogin alfa (activated) in septic shock are described, as are novel but as yet experimental approaches to the treatment of sepsis. Finally, it is i...

متن کامل

THERMAL SHOCK OF REFRACTORIES

Being brittle and having low thermal conductivity, refractories suffer damage and sometimes fail in service as a result of thermal shock. While the approach of those making fine-grained technical ceramics is to make their products sufficiently strong to withstand thermal stresses the refractory technologist is more cunning. He uses, often little known, devices to provide resistance to thermal s...

متن کامل

L-Glutamin-Induced Inhibition of Endotoxemia by Reducing Pre-Inflammatory Cytokines, Nitric Oxide, and CD40 Expression

Introduction: Researchers have been investigating the major pathogens involved in septic shock caused by lipopolysaccharide in recent years. Moreover, they have been concerned about the use of appropriate drugs to intervene with the main pathogenesis of the disease. This study aimed to investigate the effect of L-Glutamine as an HSP70 inducer in reducing pre-inflammatory cytokines and effective...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Critical Care

دوره 10  شماره 

صفحات  -

تاریخ انتشار 2006